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Cardiovascular Research

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Saint Luke's Mid America Heart Institute:

  • Is participating in close to 180 clinical research trials in all aspects of cardiovascular disease—far more than any other hospital in Kansas City.
  • Was named one of only four national Outcomes Research Centers by the American Heart Association. Together, the centers have created a national network for cardiovascular and stroke research.
  • Serves as a national model for developing successful research programs.
  • Is a national leader in cardiovascular research, with three clinical studies recognized on the American Heart Association's Top 10 list of scientific advances in heart disease and stroke.

Innovation has always been the focus at Saint Luke’s Mid America Heart Institute since its founding more than 25 years ago. As the nation’s first heart hospital, and a part of the premier health system in the Kansas City region, Saint Luke’s Mid America Heart Institute has earned a worldwide reputation for excellence in the treatment of cardiovascular disease.

Today Saint Luke’s Mid America Heart Institute is a recognized leader in many areas of cardiovascular clinical research. These programs, which enroll hundreds of patients annually in a wide array of randomized trials and registry-based research studies, are essential to our mission. Research allows us to remain on the leading edge of cardiovascular medicine, providing our patients with the most current treatments and medications.

Many of our cardiologists participate in research through the Ben D. McCallister Clinical Scholars Program, which provides funding and support for investigator initiated research.

'The World's Most Influential Minds’

In June 2014, Thomson Reuters named David J. Cohen, M.D., M.Sc., and John S. Spertus, M.D. M.P.H., as two of the most influential scientific minds in clinical medicine.

Studies published by Dr. Cohen and Dr. Spertus are consistently deemed significant by their peers, putting them in the top 1 percent of authors cited in others’ research.

Thomson Reuters recognized more than 3,200 researchers from a range of scientific fields, stating “They are performing and publishing work that their peers recognize as vital to the advancement of their science. These researchers are, undoubtedly, among the most influential scientific minds of our time.”

Dr. Cohen is medical director of cardiovascular research at the Mid America Heart Institute and the Missouri Endowed Professor of Cardiovascular Research at the University of Missouri-Kansas City. His research focuses on the economics of health care across a wide variety of applications.

Dr. Spertus is director of outcomes research at the Mid America Heart Institute and the Lauer/Missouri Endowed Chair and professor of medicine at the University of Missouri-Kansas City. His research focuses on measuring outcomes and health care quality as well as the use of information technology to guide medical decision-making. 

Centers of excellence 

In addition to participating in numerous multicenter clinical trials, Saint Luke’s cardiovascular research encompasses centers of excellence in cardiovascular outcomes research, health economics and technology assessment, noninvasive cardiac imaging, and intravascular ultrasound. These centers of excellence direct independent research and collaborate with top researchers around the world.

The most rewarding benefit of this commitment to research is seeing how it translates into the highest quality of care at the patient’s bedside. This is where research, innovation, and compassion come together in an unrivaled combination for the benefit of our patients and their families.

Saint Luke's Mid America Heart Institute 2013 research facts

  • 179 active studies
  • 1,277 patients enrolled
  • 150 publications
  • 226 abstracts/presentations
Cardiovascular Research
Saint Luke's Mid America Heart Institute

4401 Wornall Road
Kansas City, MO 64111


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